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Roberto Benigni
Roberto (segment "Strange to Meet You")
Steven Wright
Steven (segment "Strange to Meet You")
Joie Lee
Good Twin (segment "Twins")
Cinqué Lee
Evil Twin (segment "Twins") / Kitchen Guy (segment "Jack...")
Steve Buscemi
Danny (segment "Twins")
Iggy Pop
Iggy (segment "Somewhere in California")
Tom Waits
Tom (segment "Somewhere in California")
Joseph Rigano
Joe (segment "Those Things'll Kill Ya")
Vinny Vella
Vinny (segment "Those Things'll Kill Ya")
Vinny Vella, Jr.
Vinny Jr. (segment "Those Things'll Kill Ya")
Renée French
Renée (segment "Renée")
E.J. Rodriguez
Waiter (segment "Renée")