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Hugh Jackman
Tomás / Tom Creo / Tommy
Rachel Weisz
Isabel / Izzi Creo
Ellen Burstyn
Dr. Lillian Guzetti
Mark Margolis
Father Avila
Stephen McHattie
Grand Inquisitor Silecio
Fernando Hernández
Lord of Xibalba
Cliff Curtis
Captain Ariel
Sean Patrick Thomas
Antonio
Donna Murphy
Betty
Ethan Suplee
Manny
Richard McMillan
Henry
Lorne Brass
Dr. Alan Lipper