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Bill Pullman
George Bailey
Penelope Ann Miller
Mary Hatch Bailey
Nathan Lane
Clarence
Martin Landau
Pa Bailey / Mr. Potter
Sally Field
Mrs. Bailey / Narrator
Joe Mantegna
Joseph / Nick
Christian Slater
Harry Bailey / Sam Wainwright
Jerry Van Dyke
Uncle Billy
Robert Guillaume
Mr. Gower
Carol Kane
Cousin Tilly / Mrs. Hatch
Bronson Pinchot
Mr. Carter
Dan Lauria
Bert