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Robert Downey Jr.
Sherlock Holmes
Jude Law
Dr. John Watson
Rachel McAdams
Irene Adler
Mark Strong
Lord Henry Blackwood
Eddie Marsan
Inspector Lestrade
Robert Maillet
Dredger
Geraldine James
Mrs. Hudson
Kelly Reilly
Mary Morstan
William Houston
Constable Clark
Hans Matheson
Lord Coward
James Fox
Sir Thomas Rotheram
William Hope
Ambassador Standish